After establishing the Kullyspell House and Saleesh House fur trading posts in what are now Idaho and Montana, Thompson then attempted to expand further west.
The Spokane tribe, after which the county is named, means 'Children of the Sun' or 'sun people' in Salishan Explorer-geographer David Thompson, working as head of the North West Company's Columbia Department, became the first European to explore what is now the Inland Northwest. Initially, the settlers hunted predominantly bison and antelope, but after the game migrated out of the region, the native people became dependent on gathering various roots, berries, and nuts, and harvesting fish. The first humans to arrive in what is now Spokane County arrived between 12,000 and 8,000 years ago and were hunter-gatherer societies who lived off the plentiful game in the area.